One of the properties I like about reloading .45 ACP is that it is a very forgiving cartridge with relatively low pressure levels, and here are a LOT of powders that will work.
I did an analysis in Jan 2010, where I looked at powder cost per hundred rounds for 200 gr LSWC bullets. Powder prices were as of that date at
Powder Valley, Inc., and reflect the largest size cannister sold (4#, 5# or 8#).
Sorted from least expensive to most expensive. These cost calculations assume
MAXIMUM published loads for powder charge/round (most expensive case scenario).
Cost/100 = $0.77 Alliant Red Dot ---> 4.5 grains; 831 fps.
Cost/100 = $0.79 Alliant Bullseye ---> 4.6 grains; 807 fps.
Cost/100 = $0.80 Ramshot Competition ---> 4.3 grains; 896 fps.
Cost/100 = $0.83 Hodgdon Clays ---> 4.3 grains; 888 fps.
Cost/100 = $0.93 Alliant Unique ---> 5.4 grains; 790 fps.
Cost/100 = $0.98 IMR 700-X ---> 5.3 grains; 921 fps.
Cost/100 = $0.99 Accurate S1000 ---> 5.3 grains; 952 fps.
Cost/100 = $1.00 Hodgdon Titegroup ---> 5.4 grains; 957 fps.
Cost/100 = $1.05 Winchester WST ---> 5.1 grains; 910 fps.
Cost/100 = $1.08 Hodgdon HP-38 ---> 5.6 grains; 914 fps.
Cost/100 = $1.09 Accurate No.2 ---> 5.8 grains; 939 fps.
Cost/100 = $1.16 Winchester 231 ---> 5.6 grains; 914 fps.
Cost/100 = $1.28 Hodgdon Universal ---> 6.3 grains; 962 fps.
Cost/100 = $1.29 Vihtavuori N310 ---> 4 grains; 892 fps.
Cost/100 = $1.31 Ramshot ZIP ---> 6.2 grains; 997 fps.
Cost/100 = $1.34 IMR Trail Boss ---> 5.5 grains; 816 fps.
Cost/100 = $1.38 Winchester WSF ---> 6.7 grains; 970 fps.
Cost/100 = $1.45 IMR PB ---> 5.7 grains; 915 fps.
Cost/100 = $1.46 IMR 800-X ---> 7.7 grains; 958 fps.
Cost/100 = $1.49 Winchester AutoComp ---> 7.2 grains; 914 fps.
Cost/100 = $1.64 Vihtavuori N320 ---> 5.1 grains; 958 fps.
Cost/100 = $1.65 Ramshot True Blue ---> 7.8 grains; 990 fps.
Cost/100 = $1.78 Ramshot Silhouette ---> 8.4 grains; 1071 fps.
Cost/100 = $1.78 IMR SR 7625 ---> 6.9 grains; 952 fps.
Cost/100 = $1.79 IMR SR 4756 ---> 8.2 grains; 966 fps.
Cost/100 = $1.80 Accurate No.5 ---> 8.7 grains; 1025 fps.
Cost/100 = $1.87 Hodgdon HS-6 ---> 8.4 grains; 907 fps.
Cost/100 = $2.12 Vihtavuori N340 ---> 6.6 grains; 1039 fps.
Cost/100 = $2.38 Accurate No.7 ---> 11.5 grains; 1022 fps.
I've used a lot of Clays, since it burns much cleaner than Bullseye, but it does not meter as well as Bullseye. I've got about 7 lbs. of Clays left right now.
I have had a really good experience with every Ramshot powder I have tried, so I'll probably try some Ramshot Competition in the future (I really like both True Blue and Zip). My least favorite powder was AA No. 7. Noticeably sharper recoil and more than twice as expensive.