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A single punch can absolutely kill. Many times the lethal component is the victim's head striking the ground during an unprotected fall resulting from the punch, particularly if the person being hit loses consciousness. Punch + head hitting the asphalt = death, brain injury, cracked skull, and so on. It is difficult to kill a trained individual with one punch as they are less likely to take a full impact hit, know how to take a fall, and know how to avoid being knocked out. Fists and feet are very serious weapons.