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I have shot well over 5K rounds of .38 158gr LRN and 3.5gr Bullseye. BE is a very economical powder.
I've also run lots of Power Pistol, which works well too.
Its been years since i've tried any other powders as I'm content with my loads with these two. both powders also work well in .45acp, .40, 9mm.
power pistol really has some great velocity numbers if that interests you.

the only downside is they are both alliant powders. alliant has some of the worst published load data, very minimal. just one stated load and thats it.
web browsing and your own experimenting will tell you what's right. but in the end, no big deal i guess.