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Well, I'm personally not particularly fond of the idea of a red dot sight on a pistol, but that's just me........so for me it boils down to which pistol you would prefer if it was NOT equipped with a red dot sight?

I became a Glock guy about a year ago. We have owned a gen3 G19 for about 6 or 7 years now, but it is my wife's, and I hardly ever carried it. I ended up going to Glock's because that is what my wife was familiar with, and it was important to me that she be familiar with whatever I carry. She's not really a gun person, and keeping it simple is what keeps her carrying. She's "dysgunlic" when it comes to learning new platforms, whereas it comes easily to me. The Glock is dead nuts simple: draw, aim, fire, reholster.......no fancy manual of arms with a thumb safety or grip safety or a decocker or anything like that. For most of us, those things are not really an issue. For her, they are confusing. The Glock platform eliminates that confusion.

Now that said, the P320 is similar in that regard, and she could probably learn to shoot it reasonable well with some training. I've never shot one, but I've handled and dry-fired one, and in the compact size - roughly analogous to the size of the G19 - it seems like a great pistol, and I liked the trigger. But we are already invested in 5 Glocks (G43x2, G19x2, G17), so if I were to buy a P320, it would be just another polymer-framed striker-fired pistol that sits in the safe most of the time alongside the M&P, XDM, and XDS — all of which are great pistols that I don't mind carrying, but that make no sense for my "dysgunlic" wife, with whom I spend a LOT of time.