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Corbon's .380 DPX in the Kel-Tec gets high recommendations for both penetration and expansion (for a .380 round) from trainer John Farnam (who has done some gelatin testing with a variety of DPX rounds, including thru clothing and whatnot), and Marshall's gelatin testing showed it gets decent penetration for a .380 as well. As far as performance once it exits the barrel, I would think there would be little difference between the P-3AT and the LCP. As far as feeding and locking into battery, I don't know -- that could vary even between P-3ATs. You'd just have to try it and see.

Note -- Corbon DPX is different from the Corbon JHP +P. I don't recall (without running to the safe and looking at the box) if the DPX is "+P" or not, but I would not worry too much about wearing out a LCP or a P-3AT. I would not expect either of them to last as long as a full size service pistol, but so what? For the price, you can buy another one and keep it as a hot spare (or in the other pocket as a backup/NewYork reload).

Good luck.