There are two minor issues, which should not be a problem for someone who shoots this all the time, but ARE for students just trying out the gun:
1. students new to shooting often let their strong hand grip slip slightly, and the gun stops working (grip safety locks the action). This could be seen as a training reinforcement, but it also takes up more of the instructor's time staying on top of it. It seems to require a very assertive grip to engage the grip safety.
2. similar to my 1911, it is very easy for the strong-side thumb to nudge the thumb safety on, and the gun locks up. My solution, just like my DW 1911, is to use a high-thumb hold, where the thumb rides on top of the safety. I dislike having to teach that to students the first day. I would prefer they think the grip is (mostly) the same for all guns, at least until they have more experience.
However, S&W issued a recall on this gun almost as soon as it hit the shelves. They said the thumb safety had a tendency to slip to on unexpectedly. Just what I said above, except they said it was caused by firing +P ammo. I have never fired +P in this gun, so I think they got that wrong. However, they wanted to replace the safety, so I sent it in. I have not shot it enough to see if that fixed the problem.
All in all, the pros for this gun are very strong, and the cons fairly minor.
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