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For many years I was the factory rep for Aguila ammo made in Mexico and I visited the plant in Cuernavaca many times. They ordered powder to the specs they wanted and then loaded the ammo. Their ammo quality was excellent and consistent.

Rarely did they use anything like canister powders.

Before my stint as the rep for Aguila, I owned a company that re-manufactured ammo. I used many powders that most people will never see, like H-335 overscreen, HP-38 special, Ball-C#5, 5025, Bullseye #2 and #6 and a lot more. I can still buy non-canister powder (and so can you) from various suppliers. H-108 and H-116 are two examples that I use a lot. Usually you are on your own to develop safe loads, but often the supplier can get you started.

Using non-canister powders is interesting, but, potentially dangerous unless you are very experienced and have the tools to do it right.

There is no factory load that I know of in any caliber that you cannot duplicate with canister powders... use the various reloading manuals and they will get you right where you want to be and safely.