.357 magnum is a good round, but it will be necessarily limited compared to the .44 magnum. The .45 LC can be loaded up into "standard pressure" .44 magnum territory, but then it is at its limit, while the .44 can be made even hotter.......or loaded down to .44 Special territory. I think that makes the .44 Magnum the more versatile chambering. Plus, if you're shopping for commercial ammo, I think you'll likely have an easier time finding .44 magnum on the shelves than .45 LC, and probably on a par with finding .357 magnum ammo.